High-throughput detection of metal contamination in HTS outputs
Author:
Publisher
Elsevier BV
Subject
Molecular Medicine,Biochemistry,Analytical Chemistry,Biotechnology
Reference19 articles.
1. Increasing the delivery of next generation therapeutics from high throughput screening libraries;Wigglesworth;Curr Opin Chem Biol,2015
2. PAINS in the assay: chemical mechanisms of assay interference and promiscuous enzymatic inhibition observed during a sulfhydryl-scavenging HTS;Dahlin;J Med Chem,2015
3. Apparent activity in high-throughput screening: origins of compound-dependent assay interference;Thorne;Curr Opin Chem Biol,2010
4. The art of meeting palladium specifications in active pharmaceutical ingredients produced by Pd-catalyzed reactions;Garrett;Adv Synth Catal,2004
5. Metal impurities cause false positives in high-throughput screening campaigns;Hermann;ACS Med Chem Lett,2013
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