Evaluation of spin freezing versus conventional freezing as part of a continuous pharmaceutical freeze-drying concept for unit doses

Author:

De Meyer L.,Van Bockstal P.-J.,Corver J.,Vervaet C.,Remon J.P.,De Beer T.

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference20 articles.

1. Baertschi S.W., Alsante K., Reed R., 2011 Pharmaceutical stress testing: prediction drug degradation, second edition, CRC Press.

2. Comparative rates of freeze-drying for lactose and sucrose solutions as measured by photographic recording, product temperature and heat flux transducer;Chen;Pharm. Dev. Technol.,2008

3. J.A.W.M. Corver 2013. Method and system for freeze-drying injectable compositions, in particular pharmaceutical. WO2013036107.

4. In-line and real-time process monitoring of a freeze drying process using raman and NIR spectroscopy as complementary process analytical technology (PAT) tools;De Beer;J. Pharm. Sci.,2008

5. Importance of using complementary process analyzers for the process monitoring, analysis and understanding of freeze drying;De Beer;Anal. Chem.,2009

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