Hepatitis C Virus NS3 Protease Requires Its NS4A Cofactor Peptide for Optimal Binding of a Boronic Acid Inhibitor as Shown by NMR-Reference-Cited by-同舟云学术

Hepatitis C Virus NS3 Protease Requires Its NS4A Cofactor Peptide for Optimal Binding of a Boronic Acid Inhibitor as Shown by NMR

Published:2002-01 Issue:1 Volume:9 Page:79-92
ISSN:1074-5521
Container-title:Chemistry & Biology
language:en
Short-container-title:Chemistry & Biology

Author:

Archer Sharon J,Camac Daniel M,Wu Zhongren J,Farrow Neil A,Domaille Peter J,Wasserman Zelda R,Bukhtiyarova Marina,Rizzo Christopher,Jagannathan Sharada,Mersinger Lawrence J,Kettner Charles A

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,Molecular Medicine,General Medicine,Biochemistry

Reference68 articles.

1. NS3 is a serine protease required for processing of hepatitis C virus polyprotein;Tomei;J. Virol.,1993

2. Nonstructural protein 3 of the hepatitis C virus encodes a serine-type proteinase required for cleavage at the NS3/4 and NS4/5 junctions;Bartenschlager;J. Virol.,1993

3. Characterization of the hepatitis C virus-encoded serine proteinase;Grakoui;J. Virol.,1993

4. Both NS3 and NS4A are required for proteolytic processing of hepatitis C virus nonstructural proteins;Failla;J. Virol.,1994

5. Enhancement of hepatitis C virus NS3 proteinase activity by association with NS4A-specific synthetic peptides;Butkiewicz;Virology,1996

Cited by 24 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The Rise of Boron-Containing Compounds: Advancements in Synthesis, Medicinal Chemistry, and Emerging Pharmacology;Chemical Reviews;2024-02-21

2. Computational Modelling in Studies for Hepatitis C Virus (HCV) NS3 Protease;Current Topics in Medicinal Chemistry;2016-03-03

3. Boron Containing Compounds as Protease Inhibitors;Chemical Reviews;2012-04-20

4. Structural characterization of the Hepatitis C Virus NS3 protease from genotype 3a: The basis of the genotype 1b vs. 3a inhibitor potency shift;Virology;2010-09

5. Use of the Fused NS4A Peptide−NS3 Protease Domain To Study the Importance of the Helicase Domain for Protease Inhibitor Binding to Hepatitis C Virus NS3-NS4A;Biochemistry;2009-01-02