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β Cell Replacement after Gene Editing of a Neonatal Diabetes-Causing Mutation at the Insulin Locus

  • Published:2018-12 Issue:6 Volume:11 Page:1407-1415
  • ISSN:2213-6711
  • Container-title:Stem Cell Reports
  • language:en
  • Short-container-title:Stem Cell Reports

Author:

Ma Shuangyu,Viola Ryan,Sui Lina,Cherubini Valentino,Barbetti Fabrizio,Egli Dieter

Funder

American Diabetes Association

Italian Ministry of Health

Publisher

Elsevier BV

Subject

Cell Biology,Developmental Biology,Genetics,Biochemistry

Reference21 articles.

1. Insulin-producing endocrine cells differentiated in vitro from human embryonic stem cells function in macroencapsulation devices in vivo;Agulnick;Stem Cells Transl. Med.,2015

2. Neonatal diabetes: permanent neonatal diabetes and transient neonatal diabetes;Barbetti;Front. Diabetes,2017

3. New perspectives on the microvasculature of the islets of Langerhans in the rat;Bonner-Weir;Diabetes,1982

4. Seven mutations in the human insulin gene linked to permanent neonatal/infancy-onset diabetes mellitus;Colombo;J. Clin. Invest.,2008

5. Monogenic diabetes accounts for 6.3% of cases referred to 15 Italian pediatric diabetes centers during 2007 to 2012;Delvecchio;J. Clin. Endocrinol. Metab.,2017

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