The effect of mAb and excipient cryoconcentration on long-term frozen storage stability – part 2: Aggregate formation and oxidation
Author:
Funder
Novartis Pharma
Publisher
Elsevier BV
Subject
Pharmaceutical Science
Reference35 articles.
1. The ice-water interface and protein stability: a review;Arsiccio;J. Pharm. Sci.,2020
2. Heightened cold-denaturation of proteins at the ice–water interface;Arsiccio;J. Am. Chem. Soc.,2020
3. Freezing of biologicals revisited: scale, stability, excipients, and degradation stresses;Authelin;J. Pharm. Sci.,2020
4. Subvisible particle counting provides a sensitive method of detecting and quantifying aggregation of monoclonal antibody caused by freeze-thawing: insights into the roles of particles in the protein aggregation pathway;Barnard;J. Pharm. Sci.,2011
5. Cryoconcentration and 3D temperature profiles during freezing of mAb solutions in large-scale PET bottles and a novel scale-down device;Bluemel;Pharm. Res.,2020
Cited by 4 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Application of Formulation Principles to Stability Issues Encountered During Processing, Manufacturing, and Storage of Drug Substance and Drug Product Protein Therapeutics;Journal of Pharmaceutical Sciences;2023-11
2. Regulating ice formation for enhancing frozen food quality: Materials, mechanisms and challenges;Trends in Food Science & Technology;2023-09
3. High concentration formulation developability approaches and considerations;mAbs;2023-05-16
4. Stochastic ice nucleation governs the freezing process of biopharmaceuticals in vials;International Journal of Pharmaceutics;2022-09
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3