Therapeutic strategy for handling inherited retinal degenerations in a gene-independent manner using rod-derived cone viability factors

Author:

Léveillard Thierry,Fridlich Ram,Clérin Emmanuelle,Aït-Ali Najate,Millet-Puel Géraldine,Jaillard Céline,Yang Ying,Zack Donald,van-Dorsselaer Alain,Sahel José-Alain

Publisher

Elsevier BV

Subject

General Agricultural and Biological Sciences,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference52 articles.

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2. Differential effect of the rd mutation on rods and cones in the mouse retina;Carter-Dawson;Invest. Ophthalmol. Vis. Sci.,1978

3. Retinal degeneration in the rd mouse is caused by a defect in the beta subunit of rod cGMP-phosphodiesterase;Bowes;Nature,1990

4. Recessive mutations in the gene encoding the beta-subunit of rod phosphodiesterase in patients with retinitis pigmentosa;McLaughlin;Nat. Genet.,1993

5. Retinal degenerations: from cell signaling to cell therapy; pre-clinical and clinical issues;Cronin;Curr. Gene Ther.,2007

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