Pharmacological clearance of misfolded rhodopsin for the treatment of RHO ‐associated retinitis pigmentosa-Reference-Cited by-同舟云学术

Pharmacological clearance of misfolded rhodopsin for the treatment of RHO ‐associated retinitis pigmentosa

Published:2020-06-14 Issue:8 Volume:34 Page:10146-10167
ISSN:0892-6638
Container-title:The FASEB Journal
language:en
Short-container-title:FASEB j.

Author:

Liu Xujie¹²,Feng Bing¹²,Vats Abhishek¹²,Tang Hong³,Seibel William³⁴,Swaroop Manju⁵,Tawa Gregory⁵,Zheng Wei⁵,Byrne Leah¹²,Schurdak Mark⁶,Chen Yuanyuan¹²

Affiliation:

1. Department of Ophthalmology University of Pittsburgh Pittsburgh PA USA

2. McGowan Institute of Regenerative Medicine University of Pittsburgh Pittsburgh PA USA

3. Drug Discovery Center University of Cincinnati Cincinnati OH USA

4. Oncology Department Cincinnati Children’s Hospital Medical Center Cincinnati OH USA

5. National Center for Advancing Translational Sciences National Institutes of Health Bethesda MD USA

6. Drug Discovery Institute University of Pittsburgh Pittsburgh PA USA

Funder

National Institutes of Health

Center for Outcomes Research and Evaluation, Yale School of Medicine

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1096/fj.202000282R

Reference70 articles.

1. Retinitis pigmentosa

2. Misfolded Proteins and Retinal Dystrophies

3. The molecular and cellular basis of rhodopsin retinitis pigmentosa reveals potential strategies for therapy

4. Pharmacological manipulation of gain-of-function and dominant-negative mechanisms in rhodopsin retinitis pigmentosa

5. The Nature of Dominant Mutations of Rhodopsin and Implications for Gene Therapy

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