BACE1 Physiological Functions May Limit Its Use as Therapeutic Target for Alzheimer's Disease
Author:
Publisher
Elsevier BV
Subject
General Neuroscience
Reference88 articles.
1. Proteases and proteolysis in Alzheimer disease: a multifactorial view on the disease process;De Strooper;Physiol. Rev.,2010
2. Mice deficient in BACE1, the Alzheimer's β-secretase, have normal phenotype and abolished β-amyloid generation;Luo;Nat. Neurosci.,2001
3. A mutation in APP protects against Alzheimer's disease and age-related cognitive decline;Jonsson;Nature,2012
4. A recessive mutation in the APP gene with dominant-negative effect on amyloidogenesis;Di Fede;Science,2009
5. The Alzheimer disease protective mutation A2T modulates kinetic and thermodynamic properties of amyloid-β (Aβ) aggregation;Benilova;J. Biol. Chem.,2014
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