Protonated state of methotrexate, trimethoprim, and pyrimethamine bound to dihydrofolate reductase
Author:
Publisher
Elsevier BV
Subject
Molecular Biology,Biochemistry,Biophysics
Reference24 articles.
1. The Biochemistry of Folic Acid and Related Pteridines;Blakley,1969
2. Dihydrofolate Reductase: Binding of Substrates and Inhibitors and Catalytic Mechanism
3. Enzyme Inhibitors as Drugs;Hitchings,1980
4. Molecular Actions and Targets for Chemotherapeutic Agents;Blakley,1981
5. Crystal structures of Escherichia coli and Lactobacillus casei dihydrofolate reductase refined at 1.7 A resolution. I. General features and binding of methotrexate.
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