Identification of novel KCNQ4 openers by a high-throughput fluorescence-based thallium flux assay

Author:

Li Qunyi,Rottländer Mario,Xu Mingkai,Christoffersen Claus Tornby,Frederiksen Kristen,Wang Ming-Wei,Jensen Henrik Sindal

Funder

H. Lundbeck

the Ministry of Science and Technology of China

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Reference29 articles.

1. Muscarinic suppression of a novel voltage-sensitive K+ current in a vertebrate neurone;Brown;Nature,1980

2. Control of M-current;Marrion;Annu. Rev. Physiol.,1997

3. A potassium channel, the M-channel, as a therapeutic target;Surti;Curr. Opin. Invest. Drugs,2005

4. Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias;Wang;Nat. Genet.,1996

5. KCNQ1 gain-of-function mutation in familial atrial fibrillation;Chen;Science,2003

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