Farnesoid X Receptor Regulation of the NLRP3 Inflammasome Underlies Cholestasis-Associated Sepsis-Reference-Cited by-同舟云学术

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Farnesoid X Receptor Regulation of the NLRP3 Inflammasome Underlies Cholestasis-Associated Sepsis

Published:2017-04 Issue:4 Volume:25 Page:856-867.e5
ISSN:1550-4131
Container-title:Cell Metabolism
language:en
Short-container-title:Cell Metabolism

Author:

Hao Haiping,Cao Lijuan,Jiang Changtao,Che Yuan,Zhang Songyang,Takahashi Shogo,Wang Guangji,Gonzalez Frank J.

Funder

National Natural Science Foundation of China

Major New Drug Innovation and Development

Intramural Research Program of the National Cancer Institute

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Physiology

Reference45 articles.

1. Obesity and diabetes: FXR and JAK step up to BAT;Cully;Nat. Rev. Drug Discov.,2015

2. Interleukin-1beta and the autoinflammatory diseases;Dinarello;N. Engl. J. Med.,2009

3. NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals;Duewell;Nature,2010

4. Initiation and perpetuation of NLRP3 inflammasome activation and assembly;Elliott;Immunol. Rev.,2015

5. Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance;Fang;Nat. Med.,2015

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