FXR and JAK step up to BAT
Author:
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmacology,General Medicine
Link
http://www.nature.com/articles/nrd4543.pdf
Reference2 articles.
1. Fang, S. et al. Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance. Nature Med. http://dx.doi.org/10.1038/nm.3760 (2015)
2. Moisan, A. et al. White-to-brown metabolic conversion of human adipocytes by JAK activation. Nature Cell Biol. 17, 56–67 (2014)
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