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Chronic Palmitate Exposure Inhibits Insulin Secretion by Dissociation of Ca2+ Channels from Secretory Granules

  • Published:2009-12 Issue:6 Volume:10 Page:455-465
  • ISSN:1550-4131
  • Container-title:Cell Metabolism
  • language:en
  • Short-container-title:Cell Metabolism

Author:

Hoppa Michael B.,Collins Stephan,Ramracheya Reshma,Hodson Leanne,Amisten Stefan,Zhang Quan,Johnson Paul,Ashcroft Frances M.,Rorsman Patrik

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Physiology

Reference44 articles.

1. Mouse pancreatic beta-cells: tetraethylammonium blockage of the potassium permeability increase induced by depolarization;Atwater;J. Physiol.,1979

2. Fast exocytosis with few Ca(2+) channels in insulin-secreting mouse pancreatic B cells;Barg;Biophys. J.,2001

3. Vesicle pools, docking, priming, and release;Becherer;Cell Tissue Res.,2006

4. Interaction between free fatty acids and glucose metabolism;Boden;Curr. Opin. Clin. Nutr. Metab. Care,2002

5. Increased fatty acid desaturation and enhanced expression of stearoyl coenzyme A desaturase protects pancreatic beta-cells from lipoapoptosis;Busch;Diabetes,2005
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