Replacements in the exposed loop of the T15 antibody VH CDR2 affect carrier recognition of PC-containing pathogens
Author:
Publisher
Elsevier BV
Subject
Molecular Biology,Immunology
Reference41 articles.
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1. Phosphocholine-binding antibody activities are hierarchically encoded in the sequence of the heavy-chain variable region: dominance of self-association activity in the T15 idiotype;International Immunology;2013-02-04
2. Carrier-specificity of a phosphorylcholine-binding antibody requires the presence of the constant domains and is not dependent on the unique VH49 glycine or VH30 threonine residues;Journal of Immunological Methods;2007-04
3. Repertoire Shift in the Humoral Response to Phosphocholine-Keyhole Limpet Hemocyanin: VH Somatic Mutation in Germinal Center B Cells Impairs T15 Ig Function;The Journal of Immunology;2003-05-15
4. Restoration of Ig Secretion: Mutation of Germline-Encoded Residues in T15L Chains Leads to Secretion of Free Light Chains and Assembled Antibody Complexes Bearing Secretion-Impaired Heavy Chains;The Journal of Immunology;2003-02-15
5. Regulating the isotypic and idiotypic profile of an anti-PC antibody response: lessons from peptide mimics;Molecular Immunology;2002-10
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