mTORC1 and IRS1: Another Deadly Kiss
Author:
Publisher
Elsevier BV
Subject
Endocrinology,Endocrinology, Diabetes and Metabolism
Reference10 articles.
1. mTOR signaling in growth, metabolism, and disease;Saxton;Cell,2017
2. mTORC1 signaling: a double-edged sword in diabetic beta cells;Ardestani;Cell Metab.,2018
3. Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2;Copps;Diabetologia,2012
4. Serine phosphorylation by mTOR promotes IRS-1 degradation through SCFβ-TRCP E3 ubiquitin ligase;Yoneyama;iScience,2018
5. Secreted IGFBP5 mediates mTORC1-dependent feedback inhibition of IGF-1 signalling;Ding;Nat. Cell Biol.,2016
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