Thrombin active site inhibitors: chemical synthesis, in vitro and in vivo pharmacological profile of a novel and selective agent BMS-189090 and analogues-Reference-Cited by-同舟云学术

Thrombin active site inhibitors: chemical synthesis, in vitro and in vivo pharmacological profile of a novel and selective agent BMS-189090 and analogues

Published:2002-01 Issue:1 Volume:12 Page:41-44
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Das Jagabandhu,Kimball S.David,Reid Joyce A.,Wang Tammy C.,Lau Wan F.,Roberts Daniel G.M.,Seiler Steven M.,Schumacher William A.,Ogletree Martin L.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference18 articles.

1. Colman, R. W.; Marder, V. J.; Salzman, E. W.; Hirsh, J. In Hemostasis and Thrombosis; Colman, R. W., Marder, V. J., Salzman, E. W., Hirsh, J., Eds.; Lippincott: Philadelphia, 1994; pp 3–18.

2. Thrombin signalling and protease-activated receptors

3. New advances in the discovery of thrombin and factor Xa inhibitors

4. Antithrombotic therapy in cardiac disease. An emerging approach based on pathogenesis and risk.

5. Thrombin active site inhibitors

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