Replacing the pyrophosphate group of HMB-PP by a diphosphonate function abrogates Its potential to activate human γδ T cells but does not lead to competitive antagonism-Reference-Cited by-同舟云学术

Replacing the pyrophosphate group of HMB-PP by a diphosphonate function abrogates Its potential to activate human γδ T cells but does not lead to competitive antagonism

Published:2003-04 Issue:7 Volume:13 Page:1257-1260
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Reichenberg Armin,Hintz Martin,Kletschek Yvonne,Kuhl Tanja,Haug Christian,Engel Rosel,Moll Jens,Ostrovsky Dmitry N,Jomaa Hassan,Eberl Matthias

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference15 articles.

1. Y2K+1 state-of-the-art on non-peptide phosphoantigens, a novel category of immunostimulatory molecules

2. Quantitative Structure−Activity Relations for γδ T Cell Activation by Phosphoantigens

3. Identification of (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate as a major activator for human γδ T cells inEscherichia coli

4. Accumulation of a potent gammadelta T-cell stimulator after deletion of the lytB gene in Escherichia coli

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