Safety, tolerability and antitumour activity of LY2780301 (p70S6K/AKT inhibitor) in combination with gemcitabine in molecularly selected patients with advanced or metastatic cancer: a phase IB dose escalation study-Reference-Cited by-同舟云学术

Safety, tolerability and antitumour activity of LY2780301 (p70S6K/AKT inhibitor) in combination with gemcitabine in molecularly selected patients with advanced or metastatic cancer: a phase IB dose escalation study

Published:2017-09 Issue: Volume:83 Page:194-202
ISSN:0959-8049
Container-title:European Journal of Cancer
language:en
Short-container-title:European Journal of Cancer

Author:

Angevin Eric,Cassier Philippe A.,Italiano Antoine,Gonçalves Anthony,Gazzah Anas,Terret Catherine,Toulmonde Maud,Gravis Gwenaëlle,Varga Andrea,Parlavecchio Cédric,Paci Angelo,Poinsignon Vianney,Soria Jean-Charles,Drubay Damien,Hollebecque Antoine

Publisher

Elsevier BV

Subject

Cancer Research,Oncology

Reference30 articles.

1. The phosphoinositide 3-kinase pathway;Cantley;Science,2002

2. Mutations in the phosphatidylinositol 3-kinase pathway: role in tumor progression and therapeutic implications in breast cancer;Miller;Breast Cancer Res,2011

3. The emerging role of the PI3-K-Akt pathway in prostate cancer progression;Li;Prostate Cancer Prostatic Dis,2005

4. Targeting the genetic alterations of the PI3K-AKT-mTOR pathway: its potential use in the treatment of bladder cancers;Houédé;Pharmacol Ther,2015

5. Increased activation of PI3K/AKT signaling pathway is associated with cholangiocarcinoma metastasis and PI3K/mTOR inhibition presents a possible therapeutic strategy;Yothaisong;Tumour Biol,2013

Cited by 14 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. PD-1, PD-L1, IDO, CD70 and microsatellite instability as potential targets to prevent immune evasion in sarcomas;Immunotherapy;2023-10

2. Beyond Expression: Role of Phosphorylated Residues of EZH2 in Lineage Plasticity in Prostate Cancer;Endocrinology;2023-01-30

3. 3,4-Diaminopyrazolo[3,4-d]pyrimidines: a new three-component microwave-assisted synthesis and anti-leukemic properties;Organic & Biomolecular Chemistry;2023

4. Gemcitabine: An Alternative Treatment for Oxaliplatin-Resistant Colorectal Cancer;Cancers;2022-11-29

5. Beyond controlling cell size: functional analyses of S6K in tumorigenesis;Cell Death & Disease;2022-07-25