Germline findings in patients with advanced malignancies screened with paired blood–tumour testing for personalised treatment approaches

Author:

Roggia CristianaORCID,Armeanu-Ebinger Sorin,Gschwind Axel,Seibel-Kelemen Olga,Hertler Sonja,Faust Ulrike,Liebmann AlexandraORCID,Haack Tobias B.,Neumann ManuelaORCID,Bonzheim Irina,Forschner Andrea,Kopp Hans-Georg,Herster Franziska,Hartkopf AndreasORCID,Bitzer Michael,Malek Nisar P.,Brecht Ines B.,Ruhm Kristina,Möller Yvonne,Löwenheim Hubert,Ossowski StephanORCID,Rieß Olaf H.,Schroeder Christopher

Publisher

Elsevier BV

Subject

Cancer Research,Oncology

Reference35 articles.

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2. Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients;Zehir;Nat Med,2017

3. Initiative for molecular profiling and advanced cancer therapy (IMPACT): an MD Anderson precision medicine study;Tsimberidou;JCO Precis Oncol,2017

4. Prospective pan-cancer germline testing using MSK-IMPACT informs clinical translation in 751 patients with pediatric solid tumors;Fiala;Nat Cancer,2021

5. Molecularly targeted therapy based on tumour molecular profiling versus conventional therapy for advanced cancer (SHIVA): a multicentre, open-label, proof-of-concept, randomised, controlled phase 2 trial;Le Tourneau;Lancet Oncol,2015

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