Prospective pan-cancer germline testing using MSK-IMPACT informs clinical translation in 751 patients with pediatric solid tumors
-
Published:2021-02-15
Issue:3
Volume:2
Page:357-365
-
ISSN:2662-1347
-
Container-title:Nature Cancer
-
language:en
-
Short-container-title:Nat Cancer
Author:
Fiala Elise M., Jayakumaran Gowtham, Mauguen Audrey, Kennedy Jennifer A., Bouvier Nancy, Kemel YelenaORCID, Fleischut Megan Harlan, Maio Anna, Salo-Mullen Erin E., Sheehan Margaret, Arnold Angela G., Latham Alicia, Carlo Maria I.ORCID, Cadoo Karen, Murkherjee Semanti, Slotkin Emily K., Trippett Tanya, Glade Bender Julia, Meyers Paul A.ORCID, Wexler Leonard, Dela Cruz Filemon S., Cheung Nai-KongORCID, Basu Ellen, Kentsis Alex, Ortiz Michael, Francis Jasmine H., Dunkel Ira J., Khakoo Yasmin, Gilheeney Stephen, Farouk Sait Sameer, Forlenza Christopher J., Sulis Maria, Karajannis MatthiasORCID, Modak Shakeel, Gerstle Justin T., Heaton Todd E., Roberts Stephen, Yang Ciyu, Jairam Sowmya, Vijai JosephORCID, Topka SabineORCID, Friedman Danielle N., Stadler Zsofia K., Robson MarkORCID, Berger Michael F.ORCID, Schultz Nikolaus, Ladanyi Marc, O’Reilly Richard J., Abramson David H., Ceyhan-Birsoy Ozge, Zhang LiyingORCID, Mandelker Diana, Shukla Neerav N., Kung Andrew L., Offit Kenneth, Zehir AhmetORCID, Walsh Michael F.ORCID
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Oncology
Reference45 articles.
1. Howlader, N. et al. (eds.) SEER Cancer Statistics Review, 1975–2014 (National Cancer Institute, 2017). 2. Zhang, J. et al. Germline mutations in predisposition genes in pediatric cancer. N. Engl. J. Med. 373, 2336–2346 (2015). 3. Mody, R. J. et al. Integrative clinical sequencing in the management of refractory or relapsed cancer in youth. JAMA 314, 913–925 (2015). 4. Harris, M. H. et al. Multicenter feasibility study of tumor molecular profiling to inform therapeutic decisions in advanced pediatric solid tumors: the individualized cancer therapy (iCat) study. JAMA Oncol. 2, 608–615 (2016). 5. Oberg, J. A. et al. Implementation of next generation sequencing into pediatric hematology–oncology practice: moving beyond actionable alterations. Genome Med. 8, 133 (2016).
Cited by
99 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
|
|