A Phase 1 Trial of Eltrombopag in Patients Undergoing Stem Cell Transplantation after Total Body Irradiation

Author:

Liesveld Jane L.,Phillips Gordon L.,Becker Michael,Constine Louis S.,Friedberg Jonathan,Andolina Jeffrey R.,Milner Laurie A.,DeBolt Jessica,Smudzin Therese,Hyrien Ollivier,Erickson-Miller Connie L.,Johnson Brendan M.,Dawson Katie-Louise,Chen Yuhchyau

Funder

National Center for Research Resources and the National Center for Advancing Translational Sciences of the National Institutes of Health

Biomedical Advanced Research and Development Authority, Office of the Assistant Secretary for Preparedness and Response, Office of the Secretary, Department of Health and Human Services

Publisher

Elsevier BV

Subject

Transplantation,Hematology

Reference34 articles.

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2. Center for International Blood and Marrow Transplant Research. Forms manual: Post-TED (form 2450), A00425, version 2. Available from: http://www.cibmtr.org/DataManagement/TrainingReference/Manuals/DataManagement/Documents/post-ted-instruction.pdf. Accessed May 2010.

3. Clinical factors affecting engraftment and transfusion needs in SCT: a single-center retrospective analysis;Liesveld;Bone Marrow Transplant,2013

4. Simultaneous administration of TPO and G-CSF after cytoreductive treatment of rhesus monkeys prevents thrombocytopenia, accelerates platelet and red cell reconstitution, alleviates neutropenia, and promotes the recovery of immature bone marrow cells;Neelis;Exp Hematol,1997

5. Development of pancytopenia with neutralizing antibodies to thrombopoietin after multicycle chemotherapy supported by megakaryocyte growth and development factor;Basser;Blood,2002

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