STPP-UP: An alternative method for drug target identification using protein thermal stability
Author:
Funder
European Research Council
Radboud Universiteit Nijmegen
KWF Kankerbestrijding
Oncode Institute
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference19 articles.
1. Thermal proteome profiling for unbiased identification of direct and indirect drug targets using multiplexed quantitative mass spectrometry;Franken;Nat. Protoc.,2015
2. Tracking cancer drugs in living cells by thermal profiling of the proteome;Savitski;Science,2014
3. A novel antifolate suppresses growth of FPGS-deficient cells and overcomes methotrexate resistance;van der Krift;Life Sci. Alliance,2023
4. Pervasive protein thermal stability variation during the cell cycle;Becher;Cell,2018
5. Proteome integral solubility alteration: a high-throughput proteomics assay for target deconvolution;Gaetani;J. Proteome Res.,2019
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