Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action
Author:
Funder
European External Action Service
Horizon 2020
European Commission
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference37 articles.
1. The structure of ClpP at 2.3 A resolution suggests a model for ATP-dependent proteolysis;Wang;Cell,1997
2. The active ClpP protease from M. tuberculosis is a complex composed of a heptameric ClpP1 and a ClpP2 ring;Akopian;EMBO J.,2012
3. Mycobacterium tuberculosis ClpP1 and ClpP2 function together in protein degradation and are required for viability in vitro and during infection;Raju;PLoS Pathog.,2012
4. The cyclic peptide ecumicin targeting CLpC1 is active against Mycobacterium tuberculosis in vivo;Gao;Antimicrob. Agents Chemother.,2015
5. Mutation analysis of the interactions between Mycobacterium tuberculosis caseinolytic protease C1 (ClpC1) and ecumicin;Jung;Int. J. Biol. Macromol.,2017
Cited by 15 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Bacterial persisters: molecular mechanisms and therapeutic development;Signal Transduction and Targeted Therapy;2024-07-17
2. Targeted protein degradation in mycobacteria uncovers antibacterial effects and potentiates antibiotic efficacy;Nature Communications;2024-05-14
3. Structural insights into the Clp protein degradation machinery;mBio;2024-04-10
4. The Antitubercular Activities of Natural Products with Fused-Nitrogen-Containing Heterocycles;Pharmaceuticals;2024-02-06
5. Metabolites from Streptomyces aureus (VTCC43181) and Their Inhibition of Mycobacterium tuberculosis ClpC1 Protein;Molecules;2024-02-04
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3