EZH2 W113C is a gain-of-function mutation in B-cell lymphoma enabling both PRC2 methyltransferase activation and tazemetostat resistance
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference38 articles.
1. Maintaining cell identity: PRC2-mediated regulation of transcription and cancer;Comet;Nat. Rev. Cancer,2016
2. Chromatin modifiers and remodellers: regulators of cellular differentiation;Chen;Nat. Rev. Genet.,2014
3. Targeting EZH2 in cancer therapy;Yamagishi;Curr. Opin. Oncol.,2017
4. Drugging histone methyltransferases in cancer;Richart;Curr. Opin. Chem. Biol.,2020
5. EZH2 expression is associated with high proliferation rate and aggressive tumor subgroups in cutaneous melanoma and cancers of the endometrium, prostate, and breast;Bachmann;J. Clin. Oncol.,2006
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1. BMP‐ACVR1 Axis is Critical for Efficacy of PRC2 Inhibitors in B‐Cell Lymphoma;Advanced Science;2024-01-16
2. Predicting gene expression changes upon epigenomic drug treatment;F1000Research;2023-12-19
3. EZH2 inhibition: it’s all about the context;JNCI: Journal of the National Cancer Institute;2023-09-08
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5. Predicting gene expression changes upon epigenomic drug treatment;2023-07-23
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