Stereoselective pharmacokinetics of ketamine and norketamine after racemic ketamine or S-ketamine administration in Shetland ponies sedated with xylazine

Author:

Larenza M. Paula,Knobloch Monika,Landoni M. Fabiana,Levionnois Olivier L.,Kronen Peter W.,Theurillat Regula,Schatzmann Urs,Thormann Wolfgang

Publisher

Elsevier BV

Subject

General Veterinary,Animal Science and Zoology

Reference10 articles.

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2. Biopharmaceutics and Clinical Pharmacokinetics;Gibaldi,1991

3. Stereoselective pharmacokinetics of ketamine: R(-)-ketamine inhibits the elimination of S(+)-ketamine;Ihmsen;Clinical Pharmacology and Therapeutics,2001

4. Metabolism of ketamine stereoisomers by human liver microsomes;Kharasch;Anesthesiology,1992

5. Antinociceptive effects, metabolism and disposition of ketamine in ponies under target-controlled drug infusion;Knobloch;Toxicology and Applied Pharmacology,2006

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