A Quantitative Systems Pharmacology Model of the Incretin Hormones GIP and GLP1, Glucagon, Glucose, Insulin, and the Small Molecule DPP-4 Inhibitor, Linagliptin

Author:

Wu Nan,An GuohuaORCID

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference45 articles.

1. A gastric inhibitory polypeptide. I. The amino acid composition and the tryptic peptides;Brown;Can J Biochem,1971

2. The place of dipeptidyl peptidase-4 inhibitors in type 2 diabetes therapeutics: a “me too” or “the special one” antidiabetic class?;Godinho;J Diabetes Res,2015

3. Degradation of endogenous and exogenous gastric inhibitory polypeptide in healthy and in type 2 diabetic subjects as revealed using a new assay for the intact peptide;Deacon;J Clin Endocrinol Metab,2000

4. Similar elimination rates of glucagon-like peptide-1 in obese type 2 diabetic patients and healthy subjects;Vilsboll;J Clin Endocrinol Metab,2003

5. Pharmacology, physiology, and mechanisms of incretin hormone action;Campbell;Cell Metab,2013

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