Determining Maximum Sublimation Rate for a Production Lyophilizer: Computational Modeling and Comparison With Ice Slab Tests

Author:

Kshirsagar Vaibhav,Tchessalov Serguei,Kanka Frank,Hiebert David,Alexeenko Alina

Funder

Pfizer

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference22 articles.

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3. Using mathematical modeling and prior knowledge for QbD in freeze-drying processes;Fissore,2015

4. Elements of quality by design in development and scale-up of freeze-dried parenterals;Nail;Biopharm Int,2008

5. Investigation of design space for freeze-drying: use of modeling for primary drying segment of a freeze-drying cycle;Koganti;AAPS PharmSciTech,2011

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