Investigating the Impact of Drug Crystallinity in Amorphous Tacrolimus Capsules on Pharmacokinetics and Bioequivalence Using Discriminatory In Vitro Dissolution Testing and Physiologically Based Pharmacokinetic Modeling and Simulation-Reference-Cited by-同舟云学术

Investigating the Impact of Drug Crystallinity in Amorphous Tacrolimus Capsules on Pharmacokinetics and Bioequivalence Using Discriminatory In Vitro Dissolution Testing and Physiologically Based Pharmacokinetic Modeling and Simulation

Published:2018-05 Issue:5 Volume:107 Page:1330-1341
ISSN:0022-3549
Container-title:Journal of Pharmaceutical Sciences
language:en
Short-container-title:Journal of Pharmaceutical Sciences

Author:

Purohit Hitesh S.,Trasi Niraj S.,Sun Dajun D.,Chow Edwin C.Y.,Wen Hong,Zhang Xinyuan,Gao Yi,Taylor Lynne S.

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference53 articles.

1. Poor aqueous solubility—an industry wide problem in drug discovery;Lipinski;Am Pharm Rev,2002

2. Review: physical chemistry of solid dispersions;Janssens;J Pharm Pharmcol,2009

3. Solid dispersions as strategy to improve oral bioavailability of poor water soluble drugs;Vasconcelos;Drug Discov Today,2007

4. Enhanced bioavailability of a poorly soluble VR1 antagonist using an amorphous solid dispersion approach: a case study;Kennedy;Mol Pharm,2008

5. Improved human bioavailability of vemurafenib, a practically insoluble drug, using an amorphous polymer-stabilized solid dispersion prepared by a solvent-controlled coprecipitation process;Shah;J Pharm Sci,2013

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