Improved Human Bioavailability of Vemurafenib, a Practically Insoluble Drug, Using an Amorphous Polymer-Stabilized Solid Dispersion Prepared by a Solvent-Controlled Coprecipitation Process

Author:

Shah Navnit,Iyer Raman M.,Mair Hans-Juergen,Choi Duksoon,Tian Hung,Diodone Ralph,Fahnrich Karsten,Pabst-Ravot Anni,Tang Kin,Scheubel Emmanuel,Grippo Joseph F.,Moreira Sebastian A.,Go Zenaida,Mouskountakis James,Louie Theresa,Ibrahim Prabha N.,Sandhu Harpreet,Rubia Linda,Chokshi Hitesh,Singhal Dharmendra,Malick Waseem

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference59 articles.

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3. The rate of solution of solid substances in their own solutions;Noyes;J Am Chem Soc,1897

4. Solubility enhancement techniques;Vemula;Int J Pharm Sci Rev Res,2010

5. Drug release from lipid-based dosage forms;Armstrong;Int J Pharm,1980

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