Resolving Liquid-Liquid Phase Separation for a Peptide Fused Monoclonal Antibody by Formulation Optimization-Reference-Cited by-同舟云学术

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Resolving Liquid-Liquid Phase Separation for a Peptide Fused Monoclonal Antibody by Formulation Optimization

Published:2021-02 Issue:2 Volume:110 Page:738-745
ISSN:0022-3549
Container-title:Journal of Pharmaceutical Sciences
language:en
Short-container-title:Journal of Pharmaceutical Sciences

Author:

Qi Wei,Alekseychyk Larysa,Nuanmanee Noi,Temel Deniz B.,Jann Victoria,Treuheit Mike,Razinkov Vladimir

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference36 articles.

1. Investigating liquid-liquid phase separation of a monoclonal antibody using solution-state NMR spectroscopy: effect of Arg.Glu and Arg.HCl;Kheddo;Mol Pharm,2017

2. Pharmaceutical perspective on opalescence and liquid-liquid phase separation in protein solutions;Raut;Mol Pharm,2016

3. Understanding and modulating opalescence and viscosity in a monoclonal antibody formulation;Salinas;J Pharm Sci,2010

4. Arginine suppresses opalescence and liquid-liquid phase separation in IgG solutions;Oki;Int J Biol Macromol,2018

5. Challenges in the development of high protein concentration formulations;Shire;J Pharm Sci,2004

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Stability of Protein Pharmaceuticals: Recent Advances;Pharmaceutical Research;2024-06-27

2. Development of in silico models to predict viscosity and mouse clearance using a comprehensive analytical data set collected on 83 scaffold-consistent monoclonal antibodies;mAbs;2023-09-12

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