Understanding the Conditions Under Which Drugs are Transferred from the Stomach Through the Upper Small Intestine After a High-Calorie, High-Fat Meal

Author:

Dietrich ShirinORCID,Ceulemans JensORCID,Hermans ElineORCID,Argyropoulos Theodoros,Goumas Konstantinos,Vertzoni MariaORCID,Reppas ChristosORCID

Funder

European Union

National and Kapodistrian University of Athens

H2020 Marie Skłodowska-Curie Actions

Horizon 2020

Publisher

Elsevier BV

Reference33 articles.

1. In silico modeling approach for the evaluation of gastrointestinal dissolution, supersaturation, and precipitation of posaconazole;Hens;Mol Pharm,2017

2. Integration of precipitation kinetics from an in vitro, multicompartment transfer system and mechanistic oral absorption modeling for pharmacokinetic prediction of weakly basic drugs;Patel;J Pharm Sci,2019

3. Usefulness of the BioGIT system in screening for differences in early exposure in the fasted state on an a priori basis;Kostantini;Int J Pharm,2023

4. FDA. 2022. Assessing the effects of food on drugs in INDs and NDAs — clinical pharmacology considerations guidance for industry. ed.

5. EMA. 2012. EMA. European Medicines Agency updates guideline on drug interactions. ed.

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