Degradation Kinetics and Mechanism of a β-Lactam Antibiotic Intermediate, 6-Aminopenicillanic Acid, in a New Integrated Production Process

Author:

Su Min,Sun Hua,Zhao Yingying,Lu Aidang,Cao Xiaohui,Wang Jingkang

Funder

National Natural Science Foundation

Hebei Province Natural Science Foundation

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference18 articles.

1. Biotechnology of industrial antibiotics;Vandamme,1984

2. Grant NH, Wynnewood, Alburn HE. 1966. Method for producing and recovering 6-aminopenicillanic acid. Patent US 3272715.

3. Huang HT, Groton C, Seto TA. 1965. 6-Aminopenicillanic acid production. Patent US 3212995.

4. Conceptual process design of integrated fermentation, deacylation, and crystallization in the production of beta-lactam antibiotics;Engel;Ind Eng Chem Res,2009

5. Solubility of 6-aminopenicillanic acid in aqueous salt solutions from 273.15 K to 303.15 K;Su;J Chem Eng Data,2007

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