Determinants of Intestinal Availability for P-glycoprotein Substrate Drugs Estimated by Extensive Simulation With Mathematical Absorption Models
Author:
Publisher
Elsevier BV
Subject
Pharmaceutical Science
Reference51 articles.
1. The prediction of the relative importance of CYP3A/P-glycoprotein to the nonlinear intestinal absorption of drugs by advanced compartmental absorption and transit model;Takano;Drug Metab Dispos,2016
2. Regional levels of drug transporters along the human intestinal tract: co-expression of ABC and SLC transporters and comparison with Caco-2 cells;Englund;Eur J Pharm Sci,2006
3. Effect of variations in the amounts of P-glycoprotein (ABCB1), BCRP (ABCG2) and CYP3A4 along the human small intestine on PBPK models for predicting intestinal first pass;Bruyere;Mol Pharm,2010
4. Drug-drug interactions mediated through P-glycoprotein: clinical relevance and in vitro-in vivo correlation using digoxin as a probe drug;Fenner;Clin Pharmacol Ther,2009
5. Effects of itraconazole and diltiazem on the pharmacokinetics of fexofenadine, a substrate of P-glycoprotein;Shimizu;Br J Clin Pharmacol,2006
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