Effect of Variations in the Amounts of P-Glycoprotein (ABCB1), BCRP (ABCG2) and CYP3A4 along the Human Small Intestine on PBPK Models for Predicting Intestinal First Pass-Reference-Cited by-同舟云学术

Effect of Variations in the Amounts of P-Glycoprotein (ABCB1), BCRP (ABCG2) and CYP3A4 along the Human Small Intestine on PBPK Models for Predicting Intestinal First Pass

Published:2010-08-04 Issue:5 Volume:7 Page:1596-1607
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Bruyère Arnaud¹,Declèves Xavier¹,Bouzom Francois¹,Ball Kathryn¹,Marques Catie¹,Treton Xavier¹,Pocard Marc¹,Valleur Patrice¹,Bouhnik Yoram¹,Panis Yves¹,Scherrmann Jean-Michel¹,Mouly Stephane¹

Affiliation:

1. INSERM U705-CNRS UMR 7157, Faculté de Pharmacie, Université Paris Descartes, Paris, France, Department of Non-Clinical Modelling, Technologie Servier, Orléans, France, Department of Gastroenterology, Beaujon Hospital, Assistance Publique-Hôpitaux de Paris, Université Paris VII—Denis Diderot, Clichy, France, Department of Digestive Surgery, Lariboisière Hospital, Assistance Publique-Hôpitaux de Paris, Université Paris VII—Denis Diderot, Paris, France, Department of Digestive Surgery, Beaujon Hospital,...

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/mp100015x

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