Metabolic control analysis of glycolysis in trypanosomes as an approach to improve selectivity and effectiveness of drugs

Author:

Bakker Barbara M,Westerhoff Hans V,Opperdoes Fred R,Michels Paul A.M

Publisher

Elsevier BV

Subject

Molecular Biology,Parasitology

Reference41 articles.

1. Molecular mechanisms and therapeutic approaches to the treatment of African trypanosomiasis;Wang;Annu. Rev. Pharmacol. Toxicol.,1995

2. Croft SL, Urbina JA, Brun R. Chemotherapy of human leishmaniasis and trypanosomiasis. In: Hide G, Mottram JC, Coombs GH, Holmes PH, editors. Trypanosomiasis and Leishmaniasis Biology and Control, chapter 14. Oxford: CAB International, 1997:245–57.

3. Structure-based drug design: progress, results and challenges;Verlinde;Structure,1994

4. Recent advances in identifying and validating drug targets in trypanosomes and leishmanias;Barrett;Trends Microbiol.,1999

5. Compartmentation of glycolysis in trypanosomes: a potential target for new trypanocidal drugs;Michels;Biol. Cell,1988

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