Evidence for reductive activation of carcinogenic aristolochic acids by prostaglandin H synthase — 32P-postlabeling analysis of DNA adduct formation

Author:

Stiborová Marie,Frei Eva,Breuer Andrea,Wiessler Manfred,Schmeiser Heinz H

Publisher

Elsevier BV

Subject

Health, Toxicology and Mutagenesis,Genetics

Reference52 articles.

1. Y.-T. Woo, D.Y. Lai, J.C. Arcos, M.F. Argus, Chemical Induction of Cancer IIIc. Academic Press, San Diego, CA, 1988.

2. Rapidly progressive interstitial renal fibrosis in young women — association with slimming regimen including Chinese herbs;Vanherweghen;Lancet.,1993

3. Detection of DNA adducts formed by aristolochic acid in renal tissue from patients with Chinese herbs nephropathy;Schmeiser;Cancer Res.,1996

4. 32P-post-labeling analysis of DNA adducts formed by aristolochic acid in tissues from patients with Chinese herbs nephropathy;Bieler;Carcinogenesis.,1997

5. Aristolactam I a metabolite of aristolochic acid I upon activation forms an adduct found in DNA of patients with Chinese herbs nephropathy;Stiborová;Exp. Toxic. Pathol.,1999

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