Aristolactam I a metabolite of aristolochic acid I upon activation forms an adduct found in DNA of patients with Chinese herbs nephropathy

Author:

Stiborová M.,Frei E.,Breuer A.,Bieler C.A.,Schmeiser H.H.

Publisher

Elsevier BV

Subject

Cell Biology,Toxicology,General Medicine,Pathology and Forensic Medicine

Reference24 articles.

1. 32P-post-la-belling analysis of DNA adducts formed by aristolochic acid in tissues from patients with Chinese herbs nephropathy;Bieler;Carcinogenesis,1997

2. Carcinogen-DNA adduct formation in the lungs and livers of preweanling CD-1 male mice following administration of [3H]-6-nitrochrysene, [3H]-6-aminochrysene, and [3H]-1,6-dinitropyrene;Delclos;Cancer Res,1987

3. Formation and persistence of specific purine DNA-adducts by 32P-postlabeling in target and non-target organs in rats treated with aristolochic acid I;Fernando,1993

4. Aristolochic acid (NSC-50413): Phase I clinical study;Jackson;Cancer Chemother Rep,1964

5. 32P-adduct assay: comparative recoveries of structurally diverse DNA adducts in the various enhancement procedures;Gupta;Carcinogenesis,1988

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