The use of a MITO-Porter to deliver exogenous therapeutic RNA to a mitochondrial disease’s cell with a A1555G mutation in the mitochondrial 12S rRNA gene results in an increase in mitochondrial respiratory activity

Author:

Yamada Yuma,Maruyama Minako,Kita Tomoko,Usami Shin-ichi,Kitajiri Shin-ichiro,Harashima Hideyoshi

Funder

LUCA Science Inc.

Grants-in-Aid for Scientific Research

Ministry of Education, Culture, Sports, Science and Technology

MEXT

Asahi Glass Foundation

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Molecular Medicine

Reference56 articles.

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3. Stable nuclear expression of ATP8 and ATP6 genes rescues a mtDNA Complex V null mutant;Boominathan;Nucleic Acids Res.,2016

4. Artificial mitochondria transfer: current challenges, advances, and future applications;Caicedo;Stem Cells Int,2017

5. Recent advances in mitochondrial disease;Craven;Annu. Rev. Genomics Hum. Genet.,2017

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