Targeting CDK2 in cancer: challenges and opportunities for therapy
Author:
Publisher
Elsevier BV
Subject
Drug Discovery,Pharmacology
Reference81 articles.
1. CDK4/6 blockade in breast cancer: current experience and future perspectives;Zardavas;Expert Opin. Investig. Drugs,2017
2. Cyclin-dependent kinase 2 is an ideal target for ovary tumors with elevated cyclin E1 expression;Yang;Oncotarget,2015
3. Selective targeting of cyclin E1-amplified high-grade serous ovarian cancer by cyclin-dependent kinase 2 and AKT inhibition;Au-Yeung;Clin. Cancer Res.,2017
4. Cyclin-dependent kinases regulate the antiproliferative function of Smads;Matsuura;Nature,2004
5. Phosphorylation of Mcm2 by Cdc7 promotes pre-replication complex assembly during cell-cycle re-entry;Chuang;Mol. Cell,2009
Cited by 132 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Design, synthesis, and molecular docking of novel 1,3, 4-triaryl pyrazole derivatives bearing methylsulfonyl moiety with anticancer activity through dual targeting CDK2 and COX-2 enzymes;Journal of Molecular Structure;2024-04
2. Molecules inducing specific cyclin-dependent kinase degradation and their possible use in cancer therapy;Future Medicinal Chemistry;2024-01-30
3. P129, a pyrazole ring-containing isolongifolanone-derivate: synthesis and investigation of anti-glioma action mechanism;Discover Oncology;2024-01-06
4. Multiplex single-cell chemical genomics reveals the kinase dependence of the response to targeted therapy;Cell Genomics;2024-01
5. Synthesis of 6,8-diaminopurines via acid-induced cascade cyclization of 5-aminoimidazole precursors and preliminary anticancer evaluation;Organic & Biomolecular Chemistry;2024
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3