Dual-target inhibitors of bromodomain-containing protein 4 (BRD4) in cancer therapy: Current situation and future directions
Author:
Funder
National Natural Science Foundation of China
Publisher
Elsevier BV
Subject
Drug Discovery,Pharmacology
Reference59 articles.
1. The double bromodomain-containing chromatin adaptor Brd4 and transcriptional regulation;Wu;J Biol Chem,2007
2. BRD4 and cancer: going beyond transcriptional regulation;Donati;Mol Cancer,2018
3. Lysine acetylation targets protein complexes and co-regulates major cellular functions;Choudhary;Science,2009
4. Drug discovery targeting Bromodomain-Containing Protein 4;Liu;J Med Chem,2017
5. BRD4 is a histone acetyltransferase that evicts nucleosomes from chromatin;Devaiah;Nat Struct Mol Biol,2016
Cited by 17 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. LncRNA AL139294.1 can be transported by extracellular vesicles to promote the oncogenic behaviour of recipient cells through activation of the Wnt and NF-κB2 pathways in non-small-cell lung cancer;Journal of Experimental & Clinical Cancer Research;2024-01-16
2. Bromodomain‐containing protein 4 inhibition improves the efficacy of cisplatin and radiotherapy in oral squamous cell carcinoma by suppressing programmed cell death‐ligand 1 expression;Basic & Clinical Pharmacology & Toxicology;2023-12-06
3. Design, synthesis, and evaluation of 4-(3-(3,5-dimethylisoxazol-4-yl)benzyl)phthalazin-1(2H)-one derivatives: potent BRD4 inhibitors with anti-breast cancer activity;Frontiers in Pharmacology;2023-11-30
4. Selective degradation of BRD4 suppresses lung cancer cell proliferation using GSH-responsive PROTAC precursors;Bioorganic Chemistry;2023-11
5. A Combination of CPI-0610 and SAHA Induces Apoptosis through STAT3 and p38 Signalling Pathways in Diffuse Large B-cell Lymphoma Cells;Current Medicinal Chemistry;2023-10-27
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3