Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: Distinction between PHF-like immunoreactivity and microtubule binding-Reference-Cited by-同舟云学术

Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: Distinction between PHF-like immunoreactivity and microtubule binding

Published:1993-07 Issue:1 Volume:11 Page:153-163
ISSN:0896-6273
Container-title:Neuron
language:en
Short-container-title:Neuron

Author:

Biernat J.,Gustke N.,Drewes G.,Mandelkow E.-.,Mandelkow E.

Publisher

Elsevier BV

Subject

General Neuroscience

Reference52 articles.

1. A common amino acid sequence in 190-kDa microtubule-associated protein and tau for the promotion of microtubule assembly;Aizawa;J. Biol. Chem.,1989

2. Phosphorylation of tau proteins to a state like that in Alzheimer's brain is catalyzed by a calcium/calmodulin dependent kinase and modulated by phospholipids;Baudier;J. Biol. Chem.,1987

3. The switch of tau protein to an Alzheimer-like state includes the phosphorylation of two serine-proline motifs upstream of the microtubule binding region;Biernat;EMBO J.,1992

4. Regions with abundant neurofibrillary pathology in human brain exhibit a selective reduction in levels of binding-competent tau and accumulation of abnormal tau isoforms (A68 proteins);Bramblett;Lab. Invest.,1992

5. A68 proteins in Alzheimers-disease are composed of several tau isoforms in a phosphorylated state which affects their electrophoretic mobilities;Brion;Biochem. J.,1991

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