The switch of tau protein to an Alzheimer-like state includes the phosphorylation of two serine-proline motifs upstream of the microtubule binding region.-Reference-Cited by-同舟云学术

The switch of tau protein to an Alzheimer-like state includes the phosphorylation of two serine-proline motifs upstream of the microtubule binding region.

Published:1992-04 Issue:4 Volume:11 Page:1593-1597
ISSN:0261-4189
Container-title:The EMBO Journal
language:en
Short-container-title:The EMBO Journal

Author:

Biernat J.,Mandelkow E.M.,Schröter C.,Lichtenberg-Kraag B.,Steiner B.,Berling B.,Meyer H.,Mercken M.,Vandermeeren A.,Goedert M.

Publisher

Wiley

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Molecular Biology,General Neuroscience

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/j.1460-2075.1992.tb05204.x/fullpdf

Cited by 455 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Virus-like particle (VLP)-based vaccine targeting tau phosphorylated at Ser396/Ser404 (PHF1) site outperforms phosphorylated S199/S202 (AT8) site in reducing tau pathology and restoring cognitive deficits in the rTg4510 mouse model of tauopathy;2024-04-09

2. Structures of AT8 and PHF1 phosphomimetic tau: Insights into the posttranslational modification code of tau aggregation;Proceedings of the National Academy of Sciences;2024-02-26

3. Phosphorylation of Tau Protein by CDK2/cyclin A and GSK3β Recombinant Kinases: Analysis of Phosphorylation Patterns by Nuclear Magnetic Resonance Spectroscopy;Methods in Molecular Biology;2024

4. Tau seeding without tauopathy;Journal of Biological Chemistry;2024-01

5. Alzheimer’s disease and related tauopathies: disorders of disrupted neuronal identity;Trends in Neurosciences;2023-10