Nef-Mediated CD3-TCR Downmodulation Dampens Acute Inflammation and Promotes SIV Immune Evasion

Author:

Joas Simone,Sauermann Ulrike,Roshani Berit,Klippert Antonina,Daskalaki Maria,Mätz-Rensing Kerstin,Stolte-Leeb Nicole,Heigele Anke,Tharp Gregory K.,Gupta Prachi Mehrotra,Nelson Sydney,Bosinger Steven,Parodi Laura,Giavedoni Luis,Silvestri Guido,Sauter Daniel,Stahl-Hennig Christiane,Kirchhoff Frank

Funder

National Institutes of Health

German Research Foundation

Publisher

Elsevier BV

Subject

General Biochemistry, Genetics and Molecular Biology

Reference74 articles.

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4. The inability to disrupt the immunological synapse between infected human T cells and APCs distinguishes HIV-1 from most other primate lentiviruses;Arhel;J. Clin. Invest.,2009

5. Association of simian immunodeficiency virus Nef with the T-cell receptor (TCR) zeta chain leads to TCR down-modulation;Bell;J. Gen. Virol.,1998

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