Species-selective targeting of pathogens revealed by the atypical structure and active site of Trypanosoma cruzi histone deacetylase DAC2-Reference-Cited by-同舟云学术

Species-selective targeting of pathogens revealed by the atypical structure and active site of Trypanosoma cruzi histone deacetylase DAC2

Published:2021-12 Issue:12 Volume:37 Page:110129
ISSN:2211-1247
Container-title:Cell Reports
language:en
Short-container-title:Cell Reports

Author:

Marek Martin^ORCID,Ramos-Morales Elizabeth,Picchi-Constante Gisele F.A.,Bayer Theresa,Norström Carina,Herp Daniel,Sales-Junior Policarpo A.,Guerra-Slompo Eloise P.,Hausmann Kristin^ORCID,Chakrabarti Alokta,Shaik Tajith B.,Merz Annika,Troesch Edouard,Schmidtkunz Karin,Goldenberg Samuel,Pierce Raymond J.,Mourão Marina M.,Jung Manfred,Schultz Johan,Sippl Wolfgang,Zanchin Nilson I.T.^ORCID,Romier Christophe^ORCID

Publisher

Elsevier BV

Subject

General Biochemistry, Genetics and Molecular Biology

Reference85 articles.

1. HDAC inhibitors in parasitic diseases;Andrews;Immunol. Cell Biol.,2012

2. Towards histone deacetylase inhibitors as new antimalarial drugs;Andrews;Curr. Pharm. Des.,2012

3. Drug repurposing and human parasitic protozoan diseases;Andrews;Int. J. Parasitol. Drugs Drug Resist.,2014

4. Repurposing Strategy Of Atorvastatin Against Trypanosoma Cruzi: In Vitro Monotherapy And Combined Therapy With Benznidazole Exhibit Synergistic Trypanocidal Activity;Araujo-Lima;Antimicrob Agents Chemother,2018

5. Synthesis, Crystallization Studies, And In Vitro Characterization Of Cinnamic Acid Derivatives As Smhdac8 Inhibitors For The Treatment Of Schistosomiasis;Bayer;ChemMedChem,2018

Cited by 12 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Benign-by-Design SAHA Analogues for Human and Animal Vector-Borne Parasitic Diseases;ACS Medicinal Chemistry Letters;2024-08-13

2. Comparative Structure-Based Virtual Screening Utilizing Optimized AlphaFold Model Identifies Selective HDAC11 Inhibitor;International Journal of Molecular Sciences;2024-01-22

3. Molecular tools to regulate gene expression in Trypanosoma cruzi;Advances in Clinical Chemistry;2024

4. Gene editing of putative cAMP and Ca²⁺‐regulated proteins using an efficient cloning‐free CRISPR/Cas9 system in Trypanosoma cruzi;Journal of Eukaryotic Microbiology;2023-09-19

5. Multimeric structure of a subfamily III haloalkane dehalogenase‐like enzyme solved by combination of cryo‐EM and x‐ray crystallography;Protein Science;2023-09-15