Oncogenic R132 IDH1 Mutations Limit NADPH for De Novo Lipogenesis through (D)2-Hydroxyglutarate Production in Fibrosarcoma Cells-Reference-Cited by-同舟云学术

Oncogenic R132 IDH1 Mutations Limit NADPH for De Novo Lipogenesis through (D)2-Hydroxyglutarate Production in Fibrosarcoma Cells

Published:2018-10 Issue:4 Volume:25 Page:1018-1026.e4
ISSN:2211-1247
Container-title:Cell Reports
language:en
Short-container-title:Cell Reports

Author:

Badur Mehmet G.,Muthusamy Thangaselvam,Parker Seth J.,Ma Shenghong,McBrayer Samuel K.,Cordes Thekla,Magana Jose H.,Guan Kun-Liang,Metallo Christian M.

Funder

California Institute of Regenerative Medicine

NIH

Camille and Henry Dreyfus

National Science Foundation

NSF

Publisher

Elsevier BV

Subject

General Biochemistry, Genetics and Molecular Biology

Reference65 articles.

1. Hypoxia, lipids, and cancer: surviving the harsh tumor microenvironment;Ackerman;Trends Cell Biol.,2014

2. Reverse engineering the cancer metabolic network using flux analysis to understand drivers of human disease;Badur;Metab. Eng.,2018

3. Enzymatic passaging of human embryonic stem cells alters central carbon metabolism and glycan abundance;Badur;Biotechnol. J.,2015

4. Physiologic medium rewires cellular metabolism and reveals uric acid as an endogenous inhibitor of UMP synthase;Cantor;Cell,2017

5. The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway;Carbonneau;Nat. Commun.,2016

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