A Universal Approach to Optimize the Folding and Stability of Prefusion-Closed HIV-1 Envelope Trimers-Reference-Cited by-同舟云学术

A Universal Approach to Optimize the Folding and Stability of Prefusion-Closed HIV-1 Envelope Trimers

Published:2018-04 Issue:2 Volume:23 Page:584-595
ISSN:2211-1247
Container-title:Cell Reports
language:en
Short-container-title:Cell Reports

Author:

Rutten Lucy,Lai Yen-Ting,Blokland Sven,Truan Daphne,Bisschop Ilona J.M.,Strokappe Nika M.,Koornneef Annemart,van Manen Danielle,Chuang Gwo-Yu,Farney S. Katie,Schuitemaker Hanneke,Kwong Peter D.,Langedijk Johannes P.M.^ORCID

Funder

Intramural Research Program of the Vaccine Research Center, National Institute of Allergy and Infectious Diseases National Institutes of Health

IAVI Neutralizing Antibody Consortium

Janssen Pharmaceuticals

U.S. Department of Energy, Basic Energy Sciences, Office of Science

Publisher

Elsevier BV

Subject

General Biochemistry, Genetics and Molecular Biology

Reference47 articles.

1. A recombinant human immunodeficiency virus type 1 envelope glycoprotein complex stabilized by an intermolecular disulfide bond between the gp120 and gp41 subunits is an antigenic mimic of the trimeric virion-associated structure;Binley;J. Virol.,2000

2. HIV transmission. Selection bias at the heterosexual HIV-1 transmission bottleneck;Carlson;Science,2014

3. Structure-based design of a soluble prefusion-closed HIV-1 Env trimer with reduced CD4 affinity and improved immunogenicity;Chuang;J. Virol.,2017

4. Immunogenicity of stabilized HIV-1 envelope trimers with reduced exposure of non-neutralizing epitopes;de Taeye;Cell,2015

5. N-terminal substitutions in HIV-1 gp41 reduce the expression of non-trimeric envelope glycoproteins on the virus;Dey;Virology,2008

Cited by 88 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Virus-Like Particles Carrying HIV-1 Env with a Modulated Glycan Composition;Molecular Biology;2024-08

2. Design of soluble HIV-1 envelope trimers free of covalent gp120-gp41 bonds with prevalent native-like conformation;Cell Reports;2024-08

3. Neutralizing antibodies elicited in sequentially immunized macaques recognize V3 residues on altered conformations of HIV-1 Env trimer;2024-08-01

4. Natural Variation in HIV-1 Entry Kinetics Map to Specific Residues and Reveal an Interdependence Between Attachment and Fusion;2024-06-25

5. Universal paramyxovirus vaccine design by stabilizing regions involved in structural transformation of the fusion protein;Nature Communications;2024-05-31