Potent monoclonal antibodies neutralize Omicron sublineages and other SARS-CoV-2 variants

Author:

Chen Zhaochun,Zhang Peng,Matsuoka Yumiko,Tsybovsky Yaroslav,West Kamille,Santos Celia,Boyd Lisa F.,Nguyen Hanh,Pomerenke Anna,Stephens Tyler,Olia Adam S.,Zhang Baoshan,De Giorgi Valeria,Holbrook Michael R.,Gross Robin,Postnikova Elena,Garza Nicole L.,Johnson Reed F.,Margulies David H.,Kwong Peter D.,Alter Harvey J.,Buchholz Ursula J.,Lusso Paolo,Farci Patrizia

Funder

National Institute of Allergy and Infectious Diseases

Frederick National Laboratory for Cancer Research

National Institutes of Health

Vaccine Research Center

National Cancer Institute

Publisher

Elsevier BV

Subject

General Biochemistry, Genetics and Molecular Biology

Reference87 articles.

1. Antibodies targeting closely adjacent or minimally overlapping epitopes can displace one another;Abdiche;PLoS One,2017

2. New tools for the analysis and validation of cryo-EM maps and atomic models;Afonine;Acta Crystallogr. D Struct. Biol.,2018

3. SARS-CoV-2 Omicron: evasion of potent humoral responses and resistance to clinical immunotherapeutics relative to viral variants of concern;Aggarwal;medRxiv,2021

4. Extremely potent human monoclonal antibodies from COVID-19 convalescent patients;Andreano;Cell,2021

5. Assembly of combinatorial antibody libraries on phage surfaces: the gene III site;Barbas;Proc. Natl. Acad. Sci. USA,1991

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