Stereoselective adenylate deaminase (5′-adenylic acid deaminase, AMPDA)-catalyzed deamination of 5′-alkyl substituted adenosines: a comparison with the action of adenosine deaminase (ADA)
Author:
Publisher
Elsevier BV
Subject
Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Catalysis
Reference7 articles.
1. Deamination of 5′-substituted-2′,3′-isopropylidene adenosine derivatives catalyzed by adenosine deaminase (ADA, EC 3.5.4.4) and complementary enzymatic biotransformations catalyzed by adenylate deaminase (AMPDA, EC 3.5.4.6): a viable route for the preparation of 5′-substituted inosine derivatives
2. Stereoselective deamination of (5′RS)-5′-methyl-2′,3′-isopropylidene adenosine catalyzed by adenosine deaminase: preparation of diastereomerically pure 5′-methyl adenosine and inosine derivatives
3. Oligonucleotidic compounds. VIII. Synthesis of adenylyl-(5'→3')-uridine, adenylyl-(5'→3')-cytidine, guanylyl-(5'→3')-uridine, guanylyl(5'→3')-cytidine, cytidylyl-(5'→3')-cytidine, adenylyl-(5'→3')-uridylyl-(5'→3')-cytidine and related compounds
4. Approaches to isozyme-specific inhibitors. 16. A novel methyl-C5' covalent adduct of L-ethionine and .beta.,.gamma.-imido-ATP as a potent multisubstrate inhibitor of rat methionine adenosyltransferases
5. New neplanocin analogs. 1. Synthesis of 6'-modified neplanocin A derivatives as broad-spectrum antiviral agents
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1. Direct Access to Unique C‐5’‐Acyl Modified Nucleosides through Liebeskind–Srogl Cross‐Coupling Reaction;European Journal of Organic Chemistry;2021-10-27
2. Stereoselective addition of Grignard reagents to (2-methyl-5-tert-butyl)phenyl 1-thio-β-D-ribopentodialdo-1,4-furanoside derivative;Tetrahedron;2017-04
3. Structural Basis of Duplex Thermodynamic Stability and Enhanced Nuclease Resistance of 5′-C-Methyl Pyrimidine-Modified Oligonucleotides;The Journal of Organic Chemistry;2016-03-04
4. Preparation of Both C5′ Epimers of 5′-C-Methyladenosine: Reagent Control Trumps Substrate Control;The Journal of Organic Chemistry;2014-03-25
5. 2′,3′-Isopropylidene Group, A Molecular Scaffold to Study the Activity of Adenosine and Adenylate Deaminase on Adenosine Analogues Modified in the Ribose Moiety;Nucleosides, Nucleotides and Nucleic Acids;2007-11-26
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