Two complementary, diversity-driven asymmetric syntheses of a 2,2-disubstituted piperidine NK1 antagonist-Reference-Cited by-同舟云学术

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Two complementary, diversity-driven asymmetric syntheses of a 2,2-disubstituted piperidine NK1 antagonist

Published:2006-10 Issue:18 Volume:17 Page:2596-2598
ISSN:0957-4166
Container-title:Tetrahedron: Asymmetry
language:en
Short-container-title:Tetrahedron: Asymmetry

Author:

Xiao Dong,Wang Cheng,Palani Anandan,Reichard Gregory,Aslanian Robert,Shih Neng-Yang,Buevich Alexei

Publisher

Elsevier BV

Subject

Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Catalysis

Reference29 articles.

1. Selective benzylic lithiation of N-Boc-2-phenylpiperidine and pyrrolidine: expedient synthesis of a 2,2-disubstituted piperidine NK1 antagonist

2. Gem-disubstituted amino-ether based substance p antagonists

3. Stereoselective Transformation of 2H-1,4-Oxazin-2-ones into 2,(2),5,5-Tri- and Tetrasubstituted Analogues of cis-5-Hydroxy-2-piperidinemethanol and cis-5-Hydroxy-6-oxo-2-piperidinecarboxylic Acid

4. Stereoselective transformation of pyrazinones into substituted analogues of cis-5-amino-6-oxo-2-piperidinemethanol and cis-5-amino-2-piperidinemethanol

5. Asymmetric routes to substituted piperidines

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2. Reactions of Allylmagnesium Reagents with Carbonyl Compounds and Compounds with C═N Double Bonds: Their Diastereoselectivities Generally Cannot Be Analyzed Using the Felkin–Anh and Chelation-Control Models;Chemical Reviews;2020-01-06

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4. Diastereoselective Approach to cis-4-Methyl/thiol-Pipecolic Esters Based on RCM Reaction and Conjugate Michael Addition;Synthetic Communications;2014-07-28

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