Effects of nicotine infusion on the metabolism of the tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in rats

Author:

Keyler Daniel,Pentel Paul R,Kuehl Gwendolyn,Collins Greg,Murphy Sharon E

Publisher

Elsevier BV

Subject

Cancer Research,Oncology

Reference36 articles.

1. Biochemistry, biology, and carcinogenicity of tobacco-specific N-nitrosamines;Hecht;Chem. Res. Toxicol.,1998

2. Role of P450 2B6 in the metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in human liver microsomes;Murphy;14th International Symposium on Microsomes and Drug Oxidations, Sapporo, Japan, July 22–26,2002

3. Characterization of cytochrome P450 2A4 and 2A5 catalyzed 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) metabolism;Felicia;Arch. Biochem. Biophys.,2000

4. Analysis of N- and O-glucuronides of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in human urine;Carmella;Chem. Res. Toxicol.,2002

5. Individual specific glucuronidation of 4-(methylamino)-1-(3-pyridyl)-1-butanol (NNAL) by human liver microsomes;Kuehl;Proceedings of the 92nd Annual Meeting of The American Association For Cancer Research,2001

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